Relationship Between Familial Mediterranean Fever and Other Rheumatic Diseases: Coincidence or Coexistence?

Background: Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease affecting mainly ethnic groups of basin. It has been reported that it can coexist with various systemic inflammatory diseases. This study aimed to obtain information on rheumatic diseases accompany FMF and evaluate relation between such diseases.
 Methods: Eighty-four patients diagnosed have comorbidity in rheumatology clinic January 2018 - March 2020 were included this study. 
 Results: The accompanying was spondyloarthritis 36 patients. Vasculitides second 22, followed by connective tissue 13, rheumatoid arthritis 5, juvenile idiopathic 4, gout 3, hidradenitis suppurativa 1 MEFV mutation observed M694V. There no significant difference demographic characteristics clinical manifestations M694V types. Conclusions: In study, determined. Two new conditions, eosinophilic granulomatous polyangiitis, scleroderma detected. associations may be just coincidental or an extension underlying pathology. To aware association important early diagnosis appropriate treatment.